Dermatology · evaluated online

Hives
(urticaria)

Most hives respond quickly to antihistamines. Chronic hives need a structured approach — a clinician can sort out which is which.

Licensed clinicians · Available in all 50 states
Hives
Common Rx
Cetirizine, loratadine, fexofenadine, hydroxyzine
Time to feel better
Minutes to hours
Contagious
No
Telehealth fit
Yes — common

What is hives?

Hives (urticaria) are raised, itchy welts on the skin caused by histamine release. Each welt usually lasts less than 24 hours but new ones can keep appearing. Acute hives (<6 weeks) are usually triggered by allergens, infections, or stress. Chronic hives (>6 weeks) are often autoimmune.

Most acute hives resolve with antihistamines and removing the trigger. Chronic hives benefit from a longer treatment plan.

Do I have hives? Common signs

If most of these describe what you're experiencing, telehealth may be a good next step:

Raised, red or skin-colored welts that itch intensely Welts can be small or large; change shape and location Each welt fades within 24 hours but new ones appear Sometimes swelling of lips, eyelids, hands (angioedema) Worse with heat, exercise, or scratching Sometimes triggered by specific exposure (food, meds, etc.) Chronic hives: lasting more than 6 weeks
Here's how it actually works
01
Tell us what's going on5-minute online intake covers your symptoms, history, and any photos.
02
A clinician reviewsLicensed in your state. Reviews your case and asks anything needed.
03
Rx to your pharmacyIf treatment is appropriate, the prescription goes to the pharmacy you choose.

What causes it

Acute: foods (nuts, shellfish, eggs), medications (antibiotics, NSAIDs, opioids), infections, insect stings, latex. Chronic: often autoimmune (your own antibodies activate mast cells). Physical triggers: pressure, cold, heat, sunlight, exercise.

Is it contagious?

No.

Antihistamines work — but use the right one at the right dose. Many people are under-treating.

Can it be treated online?

Acute hives without breathing difficulty are well-suited to telehealth. Throat tightness, trouble breathing, or anaphylaxis needs 911. Chronic hives can be managed by telehealth with referral to allergy/immunology for refractory cases.

How hives is treated

Second-generation H1 antihistamines are first-line — cetirizine (Zyrtec), loratadine (Claritin), fexofenadine (Allegra), levocetirizine (Xyzal). Up to 4x normal dose may be needed for chronic hives. Adding an H2 blocker (famotidine) or short steroid course can help severe flares. Chronic refractory cases may need omalizumab (Xolair).

Self-care while you wait

When to skip telehealth and seek emergency care Trouble breathing, throat tightness, swelling of tongue/face, dizziness, or rapid heartbeat with hives — call 911. Could be anaphylaxis.

How long does it last?

Acute hives usually resolve in days to weeks. Chronic hives can last months to years but typically improve over time.

Frequently asked questions

Do I need to know the trigger to treat hives?

No — most acute cases respond to antihistamines even without identifying the trigger.

Why isn't Zyrtec working?

Chronic hives often need 2–4x the standard dose. Discuss higher dosing with your clinician.

Is it food allergy?

Sometimes for acute hives. Chronic hives are rarely caused by food allergy — most are autoimmune.

Can stress cause hives?

Yes, stress can trigger or worsen hives in many people.

Will allergy testing help?

For acute hives with a specific suspected trigger, yes. For chronic hives, allergy testing is usually low-yield.

This page is for general information only — not a substitute for individual medical advice. A licensed clinician reviews every intake submitted through PrescriberNow before any prescription is issued. If you're experiencing a medical emergency, call 911 or go to the nearest emergency room.

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